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article de recherche

Effects of Cyclopamine on the Viability of Articular Chondrocytes in Rats with Adjuvant Arthritis In Vitro and Part Mechanisms

Xianbing Song, Bao Zhang, Wang Taorong, Gaoyuan Wang, Yanping Huang, Ye Zhang, Meimei Liu and Xiaoyu Chen

The aim of the present study was to investigate the effect of cyclopamine, a hedgehog signaling pathway inhibitor, on Adjuvant Arthritis (AA), rat articular chondrocyte viabilit..Voir plus»

Article de révision

Endogenous Opioids and the Treatment of Multiple Sclerosis

Ian S. Zagon and Patricia J. McLaughlin

Multiple sclerosis is an autoimmune disorder of the central nervous system that affects approximately 400,000
people in the United States and 2 million individuals worldw..Voir plus»

Abstrait

Cellular therapy: A promising tool in the future of colorectal surgery

Mohammed El-Said

Cellular therapy may be the solution of challenging
problems in colorectalsurgery such as impaired healing
leading to anastomotic leakage and metastaticcolorectal<..Voir plus»

Éditorial

MiRNAs related with the cell cycle as targets and therapies in lung cancer treatment

Jason Burns

Lung cancer is the leading cause of cancer deaths worldwide. The main obstacles to this cancer's clinical success are limited therapy alternatives and resistance to existing..Voir plus»

article de recherche

In Vitro and in Silico Analysis of ADAMTS5 Transcription in Human Chondrocytes

Kazunori Hamamura, Andy Chen, Nancy Tanjung, Hui B Sun and Hiroki Yokota

Osteoarthritis is a major cause of disability in the adult population. Exercise is commonly prescribed, but the mechanisms underlying mechanotransduction of joint tissues are no..Voir plus»

Rapport de cas

Molecular Background of Cancer Recurrence

Kldiashvili Ekaterina and Bokuchava Lana

Despite significant advances in treatment and diagnostics, cancer remains a major healthcare problem worldwide. The incidence of cancer had significantly increased globally due ..Voir plus»