Aditi Kundoo
Acute Promyelocytic Leukemia (APML) is one of the distinct subtypes of AML with unique pathogenic and morphological features. It usually presents with coagulopathy and is aggressive clinically, therefore, it is imperative to diagnose APML quickly. It has commonly a distinct immunophenotypic profile with negative CD34 and HLADR negative. Here we present a case of APML with positive CD34 and HLADR positive expression and the diagnostic dilemma we faced. Our case reestablishes the importance of morphology and the pitfall in relying on flow cytometry alone without morphology.